Artemis II Commander Reid Wiseman is the last crewmember to come out of the capsule.

The process to hoist them up to awaiting Navy helicopters will begin shortly.

The four Artemis II crewmembers are emerging from the Orion capsule for the first time since beginning their mission 10 days ago.

A burst of applause and cheers could be heard in NASA's Mission Control Center as the first crew member came out.

The astronauts will get a chance to readjust to Earth's gravity on an inflatable raft known as the front porch before helicopters take them to the USS John P. Murtha.

President Donald Trump congratulated the Artemis II crew, calling it a "spectacular" trip, and said he looks forward to seeing them at the White House "soon," in a social media post following the successful splashdown.

A TV was wheeled into the roundtable dinner that the president was attending in Charlottesville, Virginia, and he watched the Artemis splashdown, according to a White House official.

The side hatch of the Orion capsule is now open, as four Navy personnel -- one for each astronaut -- enter the capsule to check on the crewmembers.

Orion's solar arrays are now fully deployed, powering the spacecraft as it continues its journey toward the moon.

In about an hour, the crew will be in high Earth orbit, and will remain there for about 24 hours to conduct systems checks.

-ABC News' Briana Alvarado