Zac Brown Band has added a very special Music City show to its tour calendar.

The group will perform at the Ryman Auditorium in Nashville, Tennessee, on Sept. 22 for an intimate, one-of-a-kind concert experience.

A portion of the proceeds from the show will benefit Hop on a Cure, a nonprofit organization that aims to fund research for amyotrophic lateral sclerosis, or ALS. The group was founded by Zac Brown Band member John Driskell "Hop" Hopkins, who revealed his own ALS diagnosis earlier this year, and his bandmates.

"Playing in Nashville, my home away from home, is always something special," the group wrote on Instagram of the upcoming show. "This particular one is meaningful because we're raising awareness and funds for one of our very own through Hop on a Cure."

The group said they've felt supported by fans ever since they announced John's diagnosis.

"We see all the love and support Hop has received thus far so we're gonna bring the house down and show folks a good time in appreciation," they added.

Tickets go on sale Friday, but members of ZBB's "Zamily" fan club will have access to a special presale beginning Tuesday.

Hopkins first revealed that he had been diagnosed with ALS back in May, saying he had "noticed some balance issues and some stiffness in my hands" in recent years.

"After careful analysis by some of the country's top neurologists, I have been diagnosed with ALS," he said in an Instagram video with his bandmates.

"Because my symptoms have been slow progressing from the start, we believe they will continue to be slow progressing going forward," he continued. "God willing, I plan to be rocking with these amazing people for many years to come."