One of the five French passengers evacuated from the MV Hondius has tested positive for hantavirus, according to French Health Minister Stephanie Rist, who spoke to French public radio on Monday morning.

The passenger showed symptoms on the plane to France, and their condition worsened overnight, Rist said. They are in a specialist infectious diseases hospital, she said.

Additionally, France has identified 22 "contact cases" -- people who may have come into contact with those infected with hantavirus, she said. These people were on two flights where someone with hantavirus was also on board and have been isolating, according to Rist.

-ABC News' Victoria Beaule

A plane carrying American passengers who were evacuated on Sunday from a hantavirus-hit cruise ship arrived early on Monday in Nebraska.

Officials on Sunday said one of the passengers arriving at Omaha's Eppley Airfield via a Department of State airlift tested positive for the virus.

That passenger and another were on the plane were traveling in the aircraft's biocontainment units "out of an abundance of caution," the Department of Health and Human Services said in a statement.

The American passenger who tested positive for hantavirus will be transported to the Nebraska Biocontainment Unit, according to Nebraska Medicine, which hosts the facility.

The individual does not have any symptoms and was separated from other passengers during the flight through biocontainment measures. They will be receiving a follow-up test, Nebraska Medicine said.

The remaining passengers will go to the National Quarantine Unit for assessment and monitoring.

The Department of Health and Human Services released a statement on Sunday saying one American has tested positive for hantavirus as the plane with 18 MV Hondius passengers is headed to the U.S.

Two of the passengers on the plane are traveling in the aircraft's biocontainment units "out of an abundance of caution," according to HHS.

The agency said that of the two, one passenger currently has mild symptoms and the other has tested PCR positive for the virus.

The plane is first going to the ASPR Regional Emerging Special Pathogen Treatment Center (RESPTC) at the University of Nebraska Medical Center before taking the passenger with mild symptoms to a second RESPTC, according to HHS.

"Upon arrival at each facility, each individual will undergo clinical assessment and receive appropriate care and support based on their condition," HHS said.

Virigina Barcones, Spain's head of Emergencies and Civil Protection, provided more details Thursday about its plans for the MV Hondius when it arrives at the Canary Islands Sunday.

"They will arrive at a completely isolated, cordoned-off area. They will board vehicles that are isolated and under guard, and will proceed to a section of the airport that will be completely cordoned off. They will board the aircraft and depart. I am saying this so that the people of the Canary Islands, the men and women living there, can rest assured that there will be absolutely no possibility of contact at any time," she said in a statement.

Barcones added that no one will be allowed to leave the boat unless they are going directly to the airport to return to their home countries.

"The United States has showed its willingness to send a plane to collect its citizens directly. Negotiations with the United Kingdom are also at an advanced stage. During meetings held throughout the day, the U.K. has also expressed its willingness to send a dedicated flight to repatriate its nationals," she said.

-ABC News' William Gretsky