The vessel is expected to arrive in Tenerife and be anchored between 4:00 and 6:00 a.m. local time Sunday, according to the health ministry in Madrid.

Fourteen Spanish passengers will be the first to be transferred to the Port of Granadilla.

-ABC News' Aicha Elhammar

An official from the Canarias Region government said that all passengers on the MV Hondius will began to evacuate within the next 24 hours.

The officials said that the government's plan is to not allow any of the passengers to put members of the population into any type of risk.

If passenger is not ready to be transferred directly to airplane of their destination, then they will not be able to leave the vessel, the officials said.

Leaving by nationality, passengers will be transferred to the port wearing full protective equipment to avoid any contact with Canarias territory and they will be escorted by a few buses via TF1 route to the airport, which will take approximately 15 minutes to reach the airport.

-ABC News' Aicha El Hammar Castano

The CDC is alerting doctors and health departments around the country to be aware of the potential for imported hantavirus cases from the cruise ship outbreak.

The agency notes that the risk of broad spread to the United States is considered extremely unlikely at this time.

There have been no confirmed hantavirus cases associated with the cruise ship in the U.S. and at least nine residents are being monitored across six states, but none have shown any signs of illness at this time.

The CDC’s advisory to doctors, via the Health Alert Network (HAN) system, reminds them that in the event of a potential hantavirus case, patients should be placed in an isolated room and health care providers should use a gown, gloves, eye protection and an N95 mask or higher level respirator.

Doctors should also consider hantavirus infections as a potential diagnosis if a patient presents with hantavirus symptoms as well as known contact with an infected individual, officials said.

-ABC News' Youri Benadjaoud

The California Health Department says they are monitoring one former passenger of the cruise ship M/V Hondius for potential hantavirus infection.

"Local health officials are in contact with the one returned passenger," the department said in a news release. "At this time, public health protocol includes daily temperature checks and assessment for any symptoms consistent with hantavirus, and direction to modify activities."

The department said it was notified by federal officials that a second California resident is still on board the cruise ship.

There are at least nine U.S. residents under monitoring across six states

No U.S. residents under monitoring have shown any signs of illness at this time.

Several American passengers from the cruise ship associated with a suspected hantavirus cluster are set to arrive at a quarantine unit in Nebraska over the next few days. Here's what to know about the facility.

The National Quarantine Unit, managed by Nebraska Medicine and the University of Nebraska Medical Center (UNMC), is the only federally funded quarantine unit in the U.S.

Its 20 single-occupancy rooms with en-suite bathrooms contain individual negative air pressure systems to safely house individuals exposed to highly hazardous communicable diseases, according to Nebraska Medicine and UNMC.

The rooms also contain exercise equipment and WiFi connectivity for patients requiring longer stays.

Nebraska Medicine and UNMC also manage the Nebraska Biocontainment Unit (NBU), which provides medical care to patients with highly hazardous communicable diseases.

“Unit personnel consists of a voluntary staff of select physicians, nursing, nursing assistants and respiratory therapists specially trained in high-level isolation and bio preparedness,” Nebraska Medicine and UNMC said on its website.

The NBU was activated in 2014 to care for U.S. citizens affected by the Ebola outbreak and medically evacuated from Africa and during the COVID-19 pandemic in 2020 to care for U.S. citizens from Wuhan, China, and the Diamond Princess Cruise ship.