Click here to learn about some of the organizations helping those affected by the earthquakes.

The two powerful earthquakes may become the most devastating in Venezuela's modern history.

Venezuela sits along the Caribbean plate. It is not part of the infamous Ring of Fire that snakes around the Pacific Ocean, where earthquakes -- especially of higher magnitude -- are relatively common.

An earthquake of this high a magnitude causes so much damage in a place like Venezuela because Venezuela’s infrastructure is not as prepared as countries along the Ring of Fire, like Japan.

The U.S. Geological Survey estimates that the death toll will likely go over 1,000 and potentially could exceed 10,000.

-ABC News’ Kenton Gewecke

The U.S. Southern Command said it is working with the State Department to support a U.S. government relief operation in Venezuela.

“Our joint forces are moving quickly to bring the unmatched airlift, logistics, and lifesaving capabilities of the U.S. military to help save lives and support the Government of Venezuela during this crisis,” a SOUTHCOM statement said.

-ABC News’ Luis Martinez

Simón Bolívar International Airport, Venezuela’s main airport in Caracas, will be closed until at least Friday, according to the Interior Ministry.

-ABC News’ Aicha El Hammar

At least 164 people were dead and another 971 people were injured after two strong earthquakes struck Venezuela on Wednesday evening, acting President Delcy Rodriguez said early on Thursday, according to The Associated Press.

-ABC News' Jamie Dorrington