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Child Abuse Dials Up the Volume on Pain

ByRADHA CHITALEABC News Medical Unit
April 03, 2008, 9:08 PM

April 4, 2008 — -- About one in 50 infants in the United States experience abuse or neglect in the first year of life, according to a government report published this week. And experts say this maltreatment can also have serious health consequences later in life.

"Kids unfortunately who are being maltreated show problems in brain development," said Ileana Arias, director of the CDC National Center for Injury Prevention and Control, who, along with the Administration for Children and Families, created the report. Maltreatment can begin "a trajectory of a number of negative outcomes, including health outcomes," according to Arias.

Now, the mechanism behind those problems may have been pinned down.

A recent study revealed a physiological connection between child abuse and feelings of intense pain. Researchers at UCLA and the University of North Carolina compared pain responses in a group of women with and without irritable bowel syndrome (IBS), with surprising results.

In a test group of 20 women, 10 suffered from IBS and 10 did not. Both groups had people with a history of abuse, both physical and sexual. When subjected to mildly painful stimuli, the subjects with both IBS and a history of abuse reported feeling more intense pain than their counterparts.

In addition to self-reported data from the test subjects, the authors were able to document the pain experience using fMRI brain imaging. This data showed that the women who reported the most pain had heightened activity in the sensation and emotion regions of the brain. In addition, the brain areas that normally help to dampen negative sensations and emotions were inhibited.

"It's the first time we are able to show a mechanistic explanation for a clinical observation," said Dr. Yehuda Ringel, an assistant professor of medicine at the University of North Carolina at Chapel Hill. "It provides patients reassurance. They are not crazy, but there is a physiological explanation for why they experience more sensation."

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