6:45
The defending 2024 champion South Carolina Gamecocks, led by head coach Dawn Staley, entered this year's tournament alongside every other Top 16 team with at least two losses, according to ESPN, setting the stage for a wide open battle.
ESPN analysts and commentators heavily favor South Carolina to take home the title again this season in a pre-tournament predictions report, despite being the No. 2 overall seed behind the Bruins.
UCLA, the No. 1 overall seed, will face off Thursday night in the Round of 64 against Southern University, who advanced over UC San Diego 68-56 earlier this week.
SOUTHERN UNIVERSITY KEEPS DANCING 🔥
— espnW (@espnW) March 20, 2025
The 16-seed Jaguars will face off against No. 1 overall seed UCLA Friday 🍿
(📸: @jaguarswbb) pic.twitter.com/st5VReFND6
Among the other top-seeded teams in the four regions, UConn, a No. 2 seed is eyeing a title for the first time since Breanna Stewart's senior year in 2016.
USC, another 1-seed, hasn't won the big dance since the team secured back-to-back titles in 1983 and 1984.
To date, no team seeded below No. 3 has ever won the NCAA women's college basketball title.
Check out the full schedule below for the women's March Madness tournament.
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/womens-march-madness-gty-jt-250321_1742570561231_hpEmbed_3x2_384.jpg\")
Click here for the complete schedule from ESPN for the women's March Madness tournament as the Round of 64 begins.
Games will be held in venues across the country, airing across an array of ESPN platforms, including ESPN+, and on ABC.
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/march-madness-gty-jt-250321_1742570399360_hpMain_4x3t_384.jpg\")
The women's tournament starts on the home courts of the top four seeds in each regional.
From there, the Sweet 16 and Elite Eight will be held in Spokane, Washington, (Regionals 1 and 4) and Birmingham, Alabama (Regionals 2 and 3).
The tournament will conclude with the Final Four in Tampa, Florida, at Amalie Arena, home of the Tampa Bay Lightning.
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