In the video, Dane explained that the initiative aims to raise $1 billion over the next three years to accelerate promising treatments for patients like him and to push toward ending the disease.

Viewers also noticed his speech was slowed -- a symptom commonly associated with ALS, according to the NIH.

His message came a day after he missed the 77th annual Emmy Awards in Los Angeles, where he had been scheduled to present alongside former \"Grey's Anatomy\" costar Jesse Williams.

Williams told E! News at the ceremony on Sunday that their friendship goes far beyond their on-screen bond.

\"We had a really great run,\" he said. \"We had a great following, and I loved working with him. You know, on and off screen, that's my brother.\"

\"Eric
Frazer Harrison/Getty Images for Prime Video
Eric Dane attends the "Countdown" Premiere and After-Party on June 18, 2025 in Los Angeles, California.
>

In June, Dane opened up in his first television interview with \"Good Morning America,\" telling Diane Sawyer that he had already lost function in his right arm and feared his left hand and legs would be next.

\"I feel like maybe a couple -- [a] few more months, and I won't have my left hand [functioning] either,\" he said at the time. \"Sobering.\"

Despite the challenges, the actor, who is also a dad of two, said he was participating in a research study and taking medication in hopes of slowing the disease's progression.

\"I'm fighting as much as I can,\" he added. \"There's so much about it that's out of my control.\"

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