Roberts spoke with Letterman about the medical obstacles she has faced and overcome. Roberts, a breast cancer survivor, was later diagnosed with myelodysplastic syndrome, or MDS, a rare blood disorder.

She underwent a bone marrow transplant in 2012, receiving donor cells from her sister, Sally-Ann. Through it all, she has maintained a positive outlook, saying she wouldn’t change a thing.

Read an Excerpt From \"Everybody's Got Something\"

\"I can look at you right now and say I am healthier and happier than I've ever been,\" Roberts, 53, said. \"That's all that matters.\"

Letterman remarked on the book's title, saying how appropriate it is. \"Nobody gets a free ride,\" he said.

\"You think you’re the only one,\" Roberts said of life's obstacles. \"And my momma would say, 'Honey, everybody's got something.' Everybody's got something, not just a challenge, but something to give to help you get through that challenge.\"

After taping the appearance, Roberts had a parting message for Letterman:

.@GMA's @RobinRoberts has a special message for Dave. Watch Robin coming up next on #LSDL pic.twitter.com/aGS5AhYF9J

— Letterman (@Letterman) April 23, 2014
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