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Photos also shared on social media show shattered windows, cars destroyed by debris and some people covered in debris.

Other photos appear to show injured people, however, it is unclear how many injuries there are from the blast.

Injuries reported and rushed to hospital in #Tianjin #Binhai Zone explosing. Strongly felt in neighbourhood. pic.twitter.com/84y1sgPwbn

— Olivier Fehr (@ofehr_en) August 12, 2015

A hospital told People’s Daily, China they have already received 300 to 400 patients with injuries.

The first blast registered at a 2.3 magnitude quake and the second was larger at a 2.9 magnitude -- the equivalent of 21 tons of TNT -- according to the China Earthquake Network Centre.

More than 100 fire trucks are at the scene where the fire is currently contained, the fire department said. Two firefighters are missing and four are injured, however, that number is expected to climb, according to the department.

Numerous high-rise buildings are out of power and some have reported chemical gas leaks as a result of the blast, CCTV America reported.

Tianjin is China’s fifth biggest city, one of four municipalities run directly by China’s central government. More than 15 million people live in Tianjin Municipality. Binhai, where the explosion happened, is home to more than half of the world’s Fortune 500 companies. Tianjin Port, the fourth biggest facility in the world in terms of goods passing through, is the maritime gateway to Beijing.

ABC News' Emily Shapiro contributed to this report.

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