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JetBlue said passengers would enjoy an in-flight bingo game and giveaways. JetBlue CEO Robin Hayes was also expected to give remarks on board.

A reception and remarks from dignitaries will greet the passengers when they deplane before JetBlue Flight 388 makes its return to the U.S.

The pilots in charge of the first pair of flights between the countries are Captain Mark Luaces and First Officer Francisco Barreras.

Luaces, born in Miami, is the son of Cuban parents who came to the U.S. as teenagers. Barreras is also the son of two Cuban parents who came to the U.S. in 1961. His great-uncle was a general manager for Pan Am in Havana. Another family member was a pilot for the Castro family.

American Airlines, the U.S.'s largest carrier, will fly to Cuba on Sept. 7.

Ten U.S.-based airlines that have now been approved for scheduled service to the island are Alaska Airlines, American Airlines, Delta Air Lines, Frontier Airlines, JetBlue, Silver Airways, Southwest Airlines, Spirit Airlines, Sun Country and United Airlines.

This is a developing story. Please check back for updates.

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