An 8-year-old girl named Saffie Rose Roussos was among those killed.

\"PHOTO:
SWNS.com
PHOTO: An undated photo of 8-year-old Saffie Roussos; she died in the Manchester, England, attack on May 22, 2017.
>

Twelve other children under the age of 16 were seriously injured, officials said.

Photos: World reactions to Manchester bombing

\"We struggle to comprehend the warped and twisted mind that sees a room packed with young children not as a scene to cherish but as an opportunity for carnage,\" May said today.

\"PHOTO:
Oli Scarffoli/AFP/Getty Images
PHOTO: Police talk to people affected by the explosion at Manchester Arena in Manchester, England, May 23, 2017.
>

Witness Joseph Harries told ABC News' \"Good Morning America\" that \"people were just trying to get out of the arena as fast as they possibly could after the blast. I was directly in front of the stage at the heart of the arena. I had exactly the same distance to get out of any of the doors.\"

\"I had my best friend with me, and I grabbed hold of her wrist and told her never let go of me,\" he said. \"We just ran. We jumped over chairs, railings to get out of the doors. We had to force open doors that wouldn't open because people were trying to get to — the entire capacity of the 20,000-person arena were trying to get out of one exit.\"

\"It felt like an eternity,\" Harries said, but it \"couldn't have been more than two, three minutes from in our seats to outside of the arena.\"

\"PHOTO:
Goodman/LNP/REX/Shutterstock
PHOTO: People help an injured woman walk near the Manchester Arena after reports of an explosion on May 22, 2017 in Manchester, England.
>

The Greater Manchester Police tweeted today that officials do not believe there are any unaccompanied children at Manchester-area hotels.

A U.S. State Department official told ABC News today that the \"U.S. Embassy in London is working to determine if any U.S. citizens were affected ... At this time, we are not aware of any U.S. citizens killed or injured.\"

\"PHOTO:
Jeff J Mitchell/Getty Images
PHOTO: Members of the public gather to attend a vigil, to honor the victims of Monday evening's terror attack, at Albert Square on May 23, 2017 in Manchester, England.
>

\"The whole nation has been shocked,\" Queen Elizabeth II said in a statement. \"I know I speak for everyone in expressing my deepest sympathy to all who have been affected by this dreadful event and especially to the families and friends of those who have died or were injured.\"

\"I want to thank all the members of the emergency services, who have responded with such professionalism and care,\" she continued. \"And I would like to express my admiration for the way the people of Manchester have responded, with humanity and compassion, to this act of barbarity.\"

\"PHOTO:
Kirsty Wigglesworth/AP Photo
PHOTO: People attend a vigil in Albert Square, Manchester, England, May 23, 2017.
>

A spokesperson for the Manchester Arena tweeted today, \"Last night, our community suffered a senseless tragedy. Our entire team's thoughts and focus are now on supporting the people affected and their families.

\"We are assisting the police in any way we can. We cannot praise the emergency services enough for their response and have been inspired by the way the people of this great city of Manchester rallied round last night and have continued to respond today. It shows the very best of this city.\"

pic.twitter.com/a5QUJtwgwp

— Manchester Arena (@ManchesterArena) May 23, 2017

ABC News' Mike Levine and Lena Masri contributed to this report.

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