\"I've spoken to Mark Rowley this morning that the two targets are still in very serious condition,\" she said. \"The policeman is talking and engaging, so I'm more optimistic for him, but it's still too early to say. This is a nerve agent. We are still treating it as very serious.\"

In an interview with ITV News Prime Minister Theresa May was asked whether she would expel Russian ambassadors from the U.K.

\"We will do what is appropriate, we will do what is right, if it is proved to be the case that this is state-sponsored,\" she said.

Both Skripals are being treated at Salisbury District Hospital.

Skripal, 66, was a former colonel in the GRU –- Russian military intelligence. He had been spying for Britain’s foreign intelligence service MI6 when he was convicted of treason in Russia in 2006. In 2010, he was part of a high-profile prisoner exchange with the United States, and sought refuge in the U.K. where he had been living a quiet life in the small city of Salisbury.

Earlier in the week, foreign secretary Boris Johnson told Parliament that the government would respond \"robustly and appropriately\" if it transpired that the attack was carried out by a foreign government on British soil.

Similarities with the 2006 poisoning of former Russian spy Alexander Litvinenko have caused speculation as to whether Russia is somehow involved.

A British inquiry into Litvinenko's murder found the Kremlin to be responsible.

A Russian Foreign Ministry spokeswoman said that foreign media had used the Skripal incident as part of an \"anti-Russia campaign.\"

The Kremlin has said that Russia has no information on the attack in Salisbury, but would cooperate with the investigation if asked by the British.

Yulia Skripal, 33, was visiting her father before the two fell suddenly ill on Sunday, reportedly after they visited Zizzi’s, an Italian restaurant in the center of the city.

Four days after the incident the restaurant remains closed and guarded around the clock by police. A nearby pub has also been closed since Tuesday.

Outside the city, in a nearby town called Amesbury, a business park has been cordoned off by police as a precaution.

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