According to election returns from the New York Secretary of State, Ocasio-Cortez holds a more than 15 percent lead over Crowley with 440 out of 449 precincts in the district reporting.

A member of Democratic Socialists of America, Ocasio-Cortez ran on a proudly leftist platform, calling to abolish the U.S. Department of Homeland Security Immigration and Customs Enforcement (ICE), fund Medicare-for-all and a federal jobs guarantee, and crack down on Wall Street.

\"PHOTO:
Scott Heins/Getty Images
PHOTO: Progressive challenger Alexandria Ocasio-Cortez is joined by New York gubenatorial candidate Cynthia Nixon at her victory party in the Bronx after upsetting incumbent Democratic Representative Joseph Crowly, June 26, 2018, in New York City.
>

Ocasio-Cortez’s grassroots campaign raised just $300,000 to Crowley’s war chest of $3,354,370, but garnered significant attention for her campaign announcement video, which went viral.

It's time for a New York that works for all of us.

On June 26th, we can make it happen - but only if we have the #CourageToChange.

It's time to get to work. Please retweet this video and sign up to knock doors + more at https://t.co/kacKFI9RtI to bring our movement to Congress. pic.twitter.com/aqKMjovEjZ

— Alexandria Ocasio-Cortez (@Ocasio2018) May 30, 2018

The primary is in a deep-blue district, all but guaranteeing Ocasio-Cortez a seat in the House come November. She would also make history as the first woman in her twenties to be elected to Congress.

Crowley had been mentioned as a potential candidate for Speaker of the House, should Democrats retake the House of Representatives.

The congressman came under fire this week for sending a proxy on Monday to debate Ocasio-Cortez on his behalf. The surrogate, former New York City Councilwoman Annabel Palma, was not a staff member on Crowley’s campaign, but a commissioner in the office of Mayor Bill De Blasio.

In an opinion piece last week, the New York Times Editorial Board – which did not make an endorsement in the race – chastised Crowley’s decision to skip the debate. Ocasio-Cortez, whose mother is Puerto Rican, told ABC News she found the choice to send a Latina surrogate “bizarre,” and noting that Crowley was just minutes away from the debate, attending an event in Queens.

\"PHOTO:
G. Ronald Lopez via Zuma Press
PHOTO: Congressman Joe Crowley addresses the audience at a prayer vigil and rally on immigration on June 22, 2018, in the Bronx borough of New York City.
>

“He didn’t show up to the Bronx,” she told ABC News. “What it gets interpreted as is absentee leadership, it’s leadership that fundamentally does not care about or understand our community.”

“The fact that he was 20 minutes away just added salt to the wound for Bronx and Queens families. And it really just sent a very clear message that he just didn’t care to be there,” she told ABC News.

There’s a bright opportunity in politics today. A new generation of Democrats is standing for action, rather than serving Mr. Trump’s agenda with a civil smile. https://t.co/UWBoEO6bsH

— Tom Steyer (@TomSteyer) June 26, 2018

Ocasio-Cortez traveled this past Sunday with progressive groups, including Voto Latino, to a detention center in West Texas along the U.S.-Mexico border to protest the Trump administration's \"zero tolerance\" policy that led to the separation of some immigrant children from their families.

\"PHOTO:
Mary Altaffer/AP
PHOTO: Alexandria Ocasio-Cortez, is photographed while being interviewed in Rockefeller Center, June 27, 2018, in New York City.
>

She also called for a “full audit” of state coffers potentially funding ICE detention centers.

“Every state needs to divest from ICE detention facilities now. Our government needs to do a full audit, and if we are providing any real estate leases to these facilities, if we are accepting any campaign contributions from these detention contractors, we have to divest,” she told ABC News last week.

Crowley conceded the race to Ocasio-Cortez Tuesday night, first by playing the ballad, \"Born to Run,\" on his guitar.

Video: Losing politician plays guitar during concession speech

His performance was followed by a more formal acknowledgement of his unexpected loss, saying in a statement, \"It has been the honor of a lifetime to represent Queens and the Bronx.\"

\"I want to congratulate Ms. Ocasio-Cortez on her victory tonight. I look forward to supporting her and all Democrats this November,\" Crowley said in the statement, \"The Trump administration is a threat to everything we stand for here in Queens and the Bronx, and if we don't win back the House this November, we will lose the nation we love. This is why we must come together. We will only be able to stop Donald Trump and the Republican Congress by working together, as a united Democratic Party.\"

President Trump also reacted to the news Tuesday night, referring to the incumbent as \"Big Trump Hater Congressman Joe Crowley.\"

Wow! Big Trump Hater Congressman Joe Crowley, who many expected was going to take Nancy Pelosi’s place, just LOST his primary election. In other words, he’s out! That is a big one that nobody saw happening. Perhaps he should have been nicer, and more respectful, to his President!

— Donald J. Trump (@realDonaldTrump) June 27, 2018

The victory also has the potential to influence the high-profile race between former Sex In the City actress progressive Cynthia Nixon, who swapped endorsements with Ocasio-Cortez just yesterday.

Nixon released a statement Tuesday night congratulating Ocasio-Cortez on her victory.

“This is a victory for the people over the powerful, for the grassroots over the establishment, for progressive Democrats over corporate Democrats. This is what happens when you give people a choice. They show up and they reject the status quo,\" Nixon said in her statement.

Sen. Bernie Sanders also congratulated her on her \"extraordinary upset.\"

Congratulations to @Ocasio2018 on her extraordinary upset victory tonight! She took on the entire local Democratic establishment in her district and won a very strong victory. She demonstrated once again what progressive grassroots politics can do.

— Bernie Sanders (@BernieSanders) June 27, 2018

ABC News' Kendall Karson contributed to this report.

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