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Trump’s campaign manager, Brad Parscale released a statement before Warren even took the stage to make the announcement, calling her a “fraud.”

\"Elizabeth Warren has already been exposed as a fraud by the Native Americans she impersonated and disrespected to advance her professional career, and the people of Massachusetts she deceived to get elected,” the statement reads. “The American people will reject her dishonest campaign and socialist ideas like the Green New Deal, that will raise taxes, kill jobs and crush America's middle-class. Only under President Trump's leadership will America continue to grow safer, secure and more prosperous.\"

Warren’s announcement comes on the heels of a tumultuous week after new fallout over her claim of Native American ancestry — a claim that, at times, has been a distraction in her political career and a potential impediment on her presidential ambitions. The issue this week arose from a Washington Post report that Warren had identified herself as \"American Indian\" on a 1986 registration card for the State Bar of Texas.

\"PHOTO:
Evan Vucci/AP
PHOTO: President Donald Trump speaks during the National Prayer Breakfast, Feb. 7, 2019, in Washington.
>

Several attendees, however, dismissed the criticisms against Warren for identifying herself on the registration card.

\"My understanding is that in her childhood she was told that’s what her background was and I don’t see anything malicious about it,\" Scott DeVow told ABC News. \"It’s a non-event.\"

Warren did not address the controversy in her speech, but a spokesperson had previously said the registration card was not an application to the bar and that it was only used for statistical purposes.

This most recent stumble in the saga over Warren's Native American heritage seemed to disrupt her momentum heading into Saturday’s announcement and it also raised questions about the durability of her campaign as she continues to confront negative headlines.

After first being elected to the Senate in 2012, Warren rose to the highest echelons of the Democratic Party by taking on Wall Street, propping up the middle class and helping create the Consumer Financial Protection Bureau under President Barack Obama after the 2008 financial crisis.

Following Saturday's announcement, Warren heads to Dover, New Hampshire. As an early primary state — and because of its proximity to Massachusetts and significance as a linchpin in presidential contests — New Hampshire is expected to be key to Warren's campaign.

ABC News' Mary Bruce, Adam Kelsey, Mariam Khan, and John Verhovek contributed to this report.

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