0:52
Sweet Home Alabama - 2002
The romantic comedy she starred in with Josh Lucas and Patrick Dempsey was another noteworthy role in her career.
Witherspoon said she wouldn't count out making a sequel, in a Facebook segment in 2016.
“I love Sweet Home Alabama too!” Witherspoon said during the Q & A on Facebook. “No, we are not making a sequel — that I know of. But if Disney wants to make a sequel, they can just call me! I would happily make Sweet Home Alabama 2.”
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/sweet-home-alabama-nc-ml-190320_hpEmbed_3x2_384.jpg\")
Lucas also said that he's discussed the idea with the actress.
\"I’ve even reached out to Reese, and I know Reese has said as well — it’s an iconic film,\" he said at an Access Live appearance in 2018. \"I would love [a sequel] because I would love to see where these characters ended up or where they are at this point in their lives.\"
Walk The Line - 2005
Witherspoon won her first and only Academy Award for best actress for her performance in \"Walk The Line\" in 2006. She played June Carter, alongside Joaquin Phoenix, who played Johnny Cash in the film.
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/reese-witherspoon-walk-the-line-2005-nc-ml-190320_hpEmbed_17x12_384.jpg\")
\"I worked really hard on #WalkTheLine, taking singing lessons for 6 months, learning to play the auto-harp (which was REALLY Fun!) and watching endless tapes of June Carter,\" she said in an Instagram post last year. \"So, when I won the on Oscar on March 5, 2006, it meant the world to me to be recognized by my peers. Overwhelmed, excited and truly humbled, I will never forget that moment.\"
View this post on InstagramA post shared by Reese Witherspoon (@reesewitherspoon) on Mar 4, 2018 at 8:16am PST
Wild - 2014
The film, based on the real-life, best-selling memoir by Cheryl Strayed, was a unique role for Witherspoon. She played a woman who sets out on a life-altering hike after losing her mother and dealing with a failed marriage.
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/reese-witherspoon-wild-ap-ml-190320_hpEmbed_3x2_384.jpg\")
Witherspoon earned an Academy Award nomination for the film in 2015.
Big Little Lies - 2017
The actress currently stars as Madeline Mackenzie on the hit HBO show. She is also an Executive Producer for it!
![\"PHOTO:](\"http://a.abcnews.com/images/GMA/reese-witherspoon-big-little-lies-2017-ht-ml-190319_hpEmbed_3x2_384.jpg\")
The second season premieres in June.
","canonicalUrl":"https://abcnews.com/GMA/Culture/happy-birthday-reese-witherspoon-stars-memorable-roles/story?id=61839142","legacySlug":"/culture/story/happy-birthday-reese-witherspoon-stars-memorable-roles-61839142","noIndexNoFollow":false},"publishTime":"08:30","publishDate":"03-22-2019","updatedTime":"11:38","updatedDate":"03-22-2019","socialImage":{"alt":"Reese Witherspoon presents onstage at MusiCares Person of the Year honoring Dolly Parton at Los Angeles Convention Center, Feb. 8, 2019, in Los Angeles.","credit":"Michael Kovac/Getty Images","ratio":"16x9","url":"https://s.abcnews.com/images/GMA/reese-witherspoon-gty-ml-190321_hpMain_16x9_1600.jpg","width":992,"height":558},"datePublished":"3/22/2019 08:30:47 GMT","video":{"live":false,"id":61839142,"headline":"Reese Witherspoon's most memorable roles","mediaAssetTitle":"reese witherspoon","description":"The actress turns 43 today!","duration":"0:52","posterImg":{"url":"https://s.abcnews.com/images/GMA/default-img-undefined.png","width":608,"height":342},"video":{"feed":"https://service-pkgabcnews.akamaized.net/opp/hls/abcnews/2019/03/190320_gma_digital_reese_,500,800,1200,1800,2500,3200,4500,.mp4.csmil/playlist.m3u8"},"playlist":["59470576","61680730","25066550"]},"relatedItems":[{"contentType":"story","date":"November 28, 2018","headline":"Reese Witherspoon's tough love approach to parenting ","section":"culture","slug":"/culture/story/reese-witherspoons-tough-love-approach-parenting-59470576","id":59470576,"image":{"alt":"Reese Witherspoon's tough love approach to parenting ","url":"https://s.abcnews.com/images/GMA/reese-wither-spoon-gty-02-jpo-181128_hpMain_4x3t_240.jpg","credit":"Marla Aufmuth/WireImage via Getty Images","ratio":"1x1"}},{"contentType":"story","date":"March 14, 2019","headline":"Check out Reese Witherspoon's stylish new shoe collection","section":"shop","slug":"/shop/story/check-reese-witherspoons-stylish-shoe-collection-61680730","id":61680730,"image":{"alt":"Check out Reese Witherspoon's stylish new shoe collection","url":"https://s.abcnews.com/images/GMA/draper-james-gingham-sandal-ht-jc-190314_hpMain_4x3t_240.jpg","credit":"Draper James","ratio":"1x1"}},{"contentType":"story","date":"August 21, 2014","headline":"'Cruel Intentions' Director Had to Get Reese Witherspoon 'Drunk' to Do Movie","section":"news","slug":"/news/story/cruel-intentions-director-reveals-reese-witherspoon-drunk-movie-25066550","id":25066550,"image":{"alt":"'Cruel Intentions' Director Had to Get Reese Witherspoon 'Drunk' to Do Movie","url":"https://s.abcnews.com/images/Entertainment/gty_cruel_intentions_mt_140821_4x3t_240.jpg","credit":"Getty Images","ratio":"1x1"}}],"relatedContentSection":"news","schemaContent":{"name":"Reese Witherspoon's most memorable roles","description":"The actress turns 43 today!","duration":"0:52","uploadDate":"03-22-2019","publication":"03-22-2019","images":"https://s.abcnews.com/images/GMA/default-img-undefined.png","url":"https://service-pkgabcnews.akamaized.net/opp/hls/abcnews/2019/03/190320_gma_digital_reese_,500,800,1200,1800,2500,3200,4500,.mp4.csmil/playlist.m3u8","contentUrl":"https://service-pkgabcnews.akamaized.net/opp/hls/abcnews/2019/03/190320_gma_digital_reese_,500,800,1200,1800,2500,3200,4500,.mp4.csmil/playlist.m3u8","link":"https://www.goodmorningamerica.com/culture/story/happy-birthday-reese-witherspoon-stars-memorable-roles-61839142"}},"playlist":[{"id":"134041491","contentType":"story","section":"news"},{"id":"134033809","contentType":"story","section":"news"},{"id":"78356537","contentType":"story","section":"news"},{"id":"133929295","contentType":"story","section":"news"},{"id":"133958398","contentType":"story","section":"news"},{"id":"133882828","contentType":"story","section":"news"},{"id":"133810954","contentType":"story","section":"news"},{"id":"133779647","contentType":"story","section":"news"},{"id":"133810835","contentType":"story","section":"news"},{"id":"133749799","contentType":"story","section":"news"},{"id":"133777519","contentType":"story","section":"news"},{"id":"133748258","contentType":"story","section":"news"},{"id":"133730535","contentType":"story","section":"news"},{"id":"133712423","contentType":"story","section":"news"},{"id":"133694181","contentType":"story","section":"news"},{"id":"133688738","contentType":"story","section":"news"},{"id":"133616358","contentType":"story","section":"news"},{"id":"133616342","contentType":"story","section":"news"},{"id":"133522899","contentType":"story","section":"news"},{"id":"133584123","contentType":"story","section":"news"}],"kvps":{"pgtyp":"article","lang":"en","sp":"goodmorningamerica","programmatic":"true","bundleId":"com.abcnews"}},"analytics":{"accountID":"wdgnewwdgnewgmaweb","ns":"gma","pageName":"gma:culture:video","pageType":"video","globalSpecVersion":"v1.08","siteDifferentiator":"gma:site","tagID":"g_page01","userABCookie":"0","section":"culture","title":"Reese Witherspoon's most memorable roles","pubTime":"04:30","pubDate":"03-22-2019","modTime":"07:38","modDate":"03-22-2019","taxonomyTags":"none","id":61839142,"editorialOtherSubjects":"","wordCount":"none","columns":"none","authors":"","authorsUnit":"none","authorsBureau":"none","subBrand":"Good Morning America","provider":"Good Morning America","videoName":"Reese Witherspoon's most memorable roles","mediaAssetTitle":"reese witherspoon","videoId":61839142,"mediaOnPage":"video","legacySlug":"/culture/story/happy-birthday-reese-witherspoon-stars-memorable-roles-61839142"},"taboola":{}},"request":{"headers":{},"httpVersion":"1.1","method":"GET","url":"/video/61839142","vary":{"host":"www.goodmorningamerica.com","cached":true,"path":"/video/61839142","forwarded-proto":"https","device":"desktop","userab":"0"}},"viewport":{"width":1260,"height":0},"user":{}};