\"I'd like to make sure that you understand that the virus only affects elephants. It poses no risks to humans or any other animals,\" Shumaker said. \"We do not know what caused this to become active in Nyah and Kalina so suddenly.\"
He said other elephants in the zoo's herd had not tested positive for the disease as of early Tuesday.
Elephants are known to live long lives, but they have considerably shorter life spans in captivity than they do in the wild.
A six-year study published in the journal Science in 2008 revealed that wild African elephants in Kenya's Amboseli National Park lived more than three times as long as their captive counterparts living in European zoos.
The researchers found obesity and mental stress to be likely factors to their untimely deaths.
ABC News' Morgan Winsor contributed to this report.
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