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The guidance comes as every state in the country is reporting an increasing number of new COVID-19 cases, according to the COVID Tracking Project, a volunteer-run data organization.

In Washington, D.C., and five states — California, Hawaii, Maine, New Hampshire and Vermont — cases are low but increasing. In the remaining 45 states as well as Guam and Puerto Rico, cases are high and staying high.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, discussed Thanksgiving travel on MSNBC this Tuesday, saying that each family is going to have to make a \"risk assessment,\" especially if you have an elderly person or someone with an underlying condition in your family.

\"You really need to make a decision,\" the nation's leading infectious disease expert said. \"Do I want to put that person at an increased risk by having people coming in from all parts of the country, usually in a crowded airport, without necessarily knowing if they're infected, without having time to get tested or time to do quarantine?\"

In recent weeks, state leaders have issued their own holiday guidance and ordered new restrictions to help curb the spread of COVID-19.

In California, officials released holiday guidelines suggesting that residents limit themselves to outdoor gatherings with people from no more than three households for no more than two hours.

Rhode Island has urged residents to avoid travel for the holidays. It also recently decreased its social gathering limit from 15 people to 10 as cases rise in the state.

Massachusetts advises short in-person visits and virtual holiday dinners with extended family and friends, \"especially if they are at higher risk for illness from COVID-19.\" Last week, amid rising cases, the state also issued new limits on gatherings at private residences, reducing them from 25 to 10, and placing a 9:30 p.m. curfew on all gatherings until further notice.

To read more about Thanksgiving safety, see here.

ABC News' Stephanie Ebbs, Sophie Tatum, Arielle Mitropoulos, Soo Rin Kim, Brian Hartman, Ben Bell and Gio Benitez contributed to this report

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