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If all goes well, administration officials predict the FDA would render its decision in days, possibly before next Tuesday. Within 24 hours of an FDA authorization, distribution of the 2.9 million doses would begin with another 2.9 million close behind and 500,000 doses held in reserve.

Each person requires two doses of the Pfizer vaccine, which is estimated to be 95% effective.

Those initial shipments will cover just a fraction of the two groups designated first in line -- front-line health care workers and residents of long-term care facilities. Governors will decide which hospitals or pharmacies get the first doses.

\"Hopefully, we will start impacting people's lives very quickly after the onset of the campaigns to immunize,\" said Moncef Slaoui, Trump's chief scientific advisor on vaccines.

\"PHOTO:
Chandan Khanna/AFP via Getty Images, FILE
PHOTO: A lab technician sorts blood samples for COVID-19 vaccination study at the Research Centers of America in Hollywood, Fla. Aug. 13, 2020.
>

Slaoui also told reporters on Wednesday that he suspects regulators will ultimately advise people with a history of severe allergic reactions not to take the vaccine following reports of two allergic reactions in the U.K.

\"My expectation is that this is new news,\" he said of the allergic reactions. And \"the expectation would be that subjects with known severe reaction -- allergic reaction -- should not take the vaccine, until we understand exactly what happened here.\"

Dr. Anthony Fauci, the nation's top infectious disease expert, said Wednesday that it's possible people will wind up excluded from receiving a particular type of vaccine, but noted there are multiple candidates in the mix.

\"If in fact, we do find out that there is a consistent issue of certain subset of people like those with allergic reactions, you'll always have other vaccine platforms that you can use,\" he said at an event hosted by the Harvard T.H. Chan School of Public Health.

Moderna also has applied for FDA authorization of its vaccine. Slaoui said those details will be published in a few days and that \"the data are impressive and compelling.\"

The U.S. is counting on the Moderna vaccine to come through to hopefully vaccinate 20 million Americans by the end of the year, increasing to 50 million total by the end of January.

\"We feel very confident that by late March, early April, the rest of the population -- those beyond the health care workers, those beyond the elderly -- will be able to receive their vaccines as well,\" Lt. Gen. Paul Ostrowski, director of supply, production and distribution for Operation Warp Speed, told ABC's \"Good Morning America.\"

ABC News' Arielle Mitropoulos, Eric Strauss, Sony Salzman and Stephanie Ebbs contributed to this report.

This report was featured in the Thursday, Dec. 10, 2020, episode of “Start Here,” ABC News’ daily news podcast.

\"Start Here\" offers a straightforward look at the day's top stories in 20 minutes. Listen for free every weekday on Apple Podcasts, Google Podcasts, Spotify, the ABC News app or wherever you get your podcasts.

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