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Experts have said glioblastoma is among the deadliest type of brain cancer. The aggressive cancer affects an estimated 13,000 in the United States every year. Senators John McCain and Ted Kennedy both died from the disease.

Through her mother's health battle, Menounos was very open about her life as a caretaker and often used her platform to raise awareness of glioblastoma.

In November 2020, Menounos asked for \"prayers\" for her parents, who were diagnosed with COVID-19.

She shared a video in April in which she spoke about her parents' battles with COVID-19 and the emotional toll on their family. \"Definitely the challenge of my life,\" she wrote about her mom and dad's COVID-19 battles.

Many expressed their condolences in the comments section of Menounos' post announcing her mother's death.

Nikki Bella wrote, \"RIP. sending you and the fam so much love light and prayers.\" Nikki's twin sister Brie echoed the sentiment. Zoe Saldana added, \"We send you so much love. Our deepest condolences Maria.\"

Catt Sadler, Menounos' former colleague at E! News, wrote, \"I know one thing for certain - your mother knew the most extraordinary love there ever was to know because of you. Your devotion to her was unparalleled. She’s with other angels now. Sending all my love.❤️💔❤️\"

Actress Ali Landry added, \"Oh Maria! I am so sorry! I have watched your journey with your beautiful Mom for months now and have been praying fervently for your family! She Is a MIRACLE!!!! Her life and strength and your love as a daughter was a gift for all of us to see!\"

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