President Joe Biden responded to the tweet, writing \"Good on ya, @BigBird. Getting vaccinated is the best way to keep your whole neighborhood safe.\"

\"PHOTO:
Kent Nishimura/Los Angeles Times via Polaris
PHOTO: Sen. Ted Cruz departs from the Senate Chamber following a vote on Wednesday, Nov. 3, 2021, in Washington.
>

The social media announcement sparked conservative backlash, including from Sen. Ted Cruz, R-Texas, accusing Big Bird of being used for \"government propaganda.\"

Government propaganda…for your 5 year old! https://t.co/lKUlomnpq1

— Ted Cruz (@tedcruz) November 6, 2021

The Centers for Disease Control and Prevention signed off on the Pfizer vaccine for children ages 5-11 last week, expanding eligibility to 28 million more Americans.

The tweet from the TV favorite, who is said to be always 6 years old, is part of the administration's big push to get kids vaccinated against COVID-19 following the Food and Drug Administration's full authorization for kids as young as 5 years old. The first lady will visit an elementary school with Surgeon General Vivek Murthy on Monday to promote the pediatric vaccinations.

Big Bird's announcement came the same day as the icon participated in a CNN town hall alongside his \"Sesame Street\" neighbors Elmo and Rosita called \"The ABCs of Covid Vaccines,\" where they answered kids' questions about the vaccine with CNN's Dr. Sanjay Gupta and anchor Erica Hill.

\"PHOTO:
HBO
PHOTO: Big Bird appears in a promotional image for season 50 of the children's show, "Sesame Street."
>

Cruz has received the COVID-19 vaccine himself but says he is against vaccine mandates. The Texas senator continued to criticize Big Bird's announcement on Twitter.

Big Bird coming over to vaccinate your kids. pic.twitter.com/LQODCO3GKg

— Ted Cruz (@tedcruz) November 7, 2021

In response to ABC News' request for comment, Cruz's office pointed to previous tweets from the senator encouraging parents to make their own decisions regarding their children's health.

\"PHOTO:
Hannah Beier/Reuters
PHOTO: Coraline Carvalho, 6, receives the Pfizer coronavirus disease vaccine while being held by her mother in Collegeville, Pa., Nov. 6, 2021.
>

This is not the first time the \"Sesame Street\" character has weighed in on vaccines for children. After Cruz accused the administration of using Big Bird to spread \"propaganda,\" a 1972 \"Sesame Street\" clip showing Big Bird lining up for the measles vaccine began gaining traction online.

Big Bird gets vaccinated, 1972 pic.twitter.com/M2mdmmjZ0N

— Muppet Wiki (@MuppetWiki) November 6, 2021

Newsmax host Steve Cortes joined Cruz in attacking the Big Bird tweet, calling it \"evil.\"

Others came to the \"Sesame Street\" character's defense. Former President Donald Trump's niece, and one of his frequent critics, Mary Trump, defended Big Bird and pointed out Cruz's vaccination status.

Big Bird is kind, compassionate, empathetic, loving, adored, and vaccinated. Ted Cruz is . . . vaccinated.

— Mary L Trump (@MaryLTrump) November 8, 2021
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