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Ayala said about 25 to 30 homes were destroyed in an area just north of Winterset.

\"This is the worst that anyone's seen in quite a long time,\" he added.

The Red Cross has set up an emergency center in New Bridge Church in Winterset, officials said.

\"Our hearts and prayers go out to all those affected by today’s tragic storms that ripped through our state,\" Iowa Gov. Kim Reynolds wrote on Twitter.

Reynolds also issued a disaster proclamation in Madison County.

ABC News' Darren Reynolds and Keith Harden contributed to this report.

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