• Video
  • Shop
  • Culture
  • Family
  • Wellness
  • Food
  • Living
  • Style
  • Travel
  • News
  • Book Club
  • Newsletter
  • Privacy Policy
  • Your US State Privacy Rights
  • Children's Online Privacy Policy
  • Interest-Based Ads
  • Terms of Use
  • Do Not Sell My Info
  • Contact Us
  • © 2026 ABC News
  • Wellness

Gender-affirming care for trans youth improves mental health: Study

1:01
Gender-affirming care for trans youth improves mental health: Study
STOCK IMAGE/Getty Images
ByKiara Alfonseca and Nicole Wetsman
January 18, 2023, 10:00 PM

Gender-affirming hormone therapy improves the mental health of transgender adolescents and teenagers, a new study released Wednesday in the New England Journal of Medicine showed.

The study tracked over 300 trans and nonbinary youth across the country for two years as they took testosterone or estradiol to help their physical appearance align more closely with their gender. The participants were in various stages of puberty.

The report found that depression and anxiety symptoms decreased for trans adolescents and teenagers, and life satisfaction increased after starting and continuing gender-affirming hormone therapy.

PHOTO: patient getting an injection in the leg.
STOCK PHOTO/Getty Images

Many studies over the past few years have reached similar conclusions, but this is one of the larger studies to date.

The findings highlight what activists say are the dangers of denying trans adolescents and teens gender-affirming medical care, which has been under attack in states across the country.

At least 11 states have introduced bills for the 2023 legislative sessions that would ban or restrict the use of hormone therapy for trans people. States like Arkansas, Tennessee, Alabama, Arizona, Florida and Texas have implemented policies or laws that restrict gender-affirming care broadly for trans youth.

Related Articles

MORE: Amid anti-LGBTQ efforts, transgender community finds joy in 'chosen families'

Some introduced bills no longer affect just minors – some states like Oklahoma introduced prospective bans into adulthood, restricting access to this care until the age of 26.

PHOTO: Transgender holding two transgender flags in the sky
STOCK IMAGE/Getty Images

Top national medical associations such as the American Medical Association, American Academy of Child and Adolescent Psychiatry, and American Academy of Pediatrics support gender-affirming care as safe, effective, and proven to save young people's lives.

Related Articles

MORE: Drag queens refuse to 'hide' amid anti-LGBTQ hate, threats and Colorado Springs shooting

The team behind this study is also researching the effects of puberty blockers, which have also come under scrutiny by legislators.

Puberty blockers suppress puberty for transgender children so they don't have to experience the effects of puberty that do not align with their gender, as defined by Planned Parenthood.

That data has not yet been released. However, puberty blockers are considered to be a safe treatment for children, and have also been used for non-transgender related care.

Up Next in Wellness—

Adolescent and young adult cancers increase risk of developing future cancers

April 13, 2026

Teen with kidney disease finds donor living minutes away

April 10, 2026

Her battle with cancer went viral. After her death, the impact of her advocacy is still felt

April 8, 2026

Gabrielle Union shares emotional tribute after dad dies following dementia battle

April 6, 2026

Shop GMA Favorites

ABC will receive a commission for purchases made through these links.

Sponsored Content by Taboola

The latest lifestyle and entertainment news and inspiration for how to live your best life - all from Good Morning America.
  • Contests
  • Terms of Use
  • Privacy Policy
  • Do Not Sell My Info
  • Children’s Online Privacy Policy
  • Advertise with us
  • Your US State Privacy Rights
  • Interest-Based Ads
  • About Nielsen Measurement
  • Press
  • Feedback
  • Shop FAQs
  • ABC News
  • ABC
  • All Videos
  • All Topics
  • Sitemap

© 2026 ABC News
  • Privacy Policy— 
  • Your US State Privacy Rights— 
  • Children's Online Privacy Policy— 
  • Interest-Based Ads— 
  • Terms of Use— 
  • Do Not Sell My Info— 
  • Contact Us— 

© 2026 ABC News