About 650 people in New Haven, Connecticut, received Pfizer vaccine doses that had been "improperly" stored, which may have made them less effective, the city said. 

“After consulting with Pfizer and the Connecticut Department of Public Health it was recommended that those who received the improperly stored Pfizer vaccine or booster get re-vaccinated as soon as they can,” Maritza Bond, the city's health director, said in a statement on Friday.  

The shots were given between Dec. 23, 2021, and Feb. 7, 2022, at a city clinic on Meadow Street, officials said.

 
The doses were stored at colder temperatures for longer than usual, perhaps making them less effective, officials said. They said no health issues had been reported by those who received the doses.  

“This issue was identified this week when the Health Department was conducting an inventory of our vaccines,” Mayor Justin Elicker said in a statement. “Following this notification, action was taken to investigate the issue and the Director of Health immediately reached out to the State Department of Public Health as well the vaccine manufacturer, Pfizer.”  

Elicker said the city planned on Saturday to begin notifying those who received the doses.

The U.S. Supreme Court denied a request for emergency intervention by a small group of teachers who challenged New York City’s vaccination mandate for public school employees.

Justice Sonia Sotomayor denied the application for an emergency injunction without any comment.

Without the injunction, the public school employees said they’re facing termination Monday unless they waive their right to continue this litigation or violate their sincere religious beliefs.

-ABC News' Aaron Katersky and Devin Dwyer

Pfizer said it has postponed its application to the FDA to expand the use of its COVID-19 vaccine for kids under 5.

Pfizer instead will continue with its study on the three-dose vaccine and seek authorization when that data is available.

"We believe additional information regarding the ongoing evaluation of a third dose should be considered as part of our decision-making for potential authorization," Pfizer said.

Dr. Peter Marks, the FDA’s vaccine chief, told reporters Friday, “We realized now, in data that came in very rapidly because of the large number of cases of omicron, that at this time, it makes sense for us to wait until we have the data from the evaluation of a third dose before taking action."

Marks acknowledged that the change was “late breaking” -- the FDA’s committee of independent advisers was scheduled to review and vote on authorizing the vaccine next week -- but said the job of the FDA was to “adjust” to new data amid an unpredictable virus.

“The data that we saw made us realize that we needed to see data from a third dose as in the ongoing trial in order to make the term determination that we could proceed with doing an authorization,” Marks said.

Pfizer has predicted it will be able to submit data on the third dose in early April.

-ABC News' Eric M. Strauss, Cheyenne Haslett

The FDA has authorized a new monoclonal antibody treatment from Eli Lilly called bebtelovimab, an injection which has shown to hold up against omicron and the BA.2 subvariant. 

As with other monoclonal therapies, this is for COVID-19 patients early on in their infection who are at high risk for getting severely ill, to help keep them from getting sicker and help keep them out of the hospital. 

The Biden administration said it has purchased 600,000 doses for roughly $720 million in anticipation of bebtelovimab getting an emergency use authorization from the FDA. 

The plan is to get about 300,000 doses this month and another 300,000 in March. The contract also includes a future option for 500,000 more doses if necessary.  

-ABC News' Sasha Pezenik

Canada's capital declared a state of emergency on Sunday because of trucker-led protests against COVID-19 vaccine mandates and other pandemic-related restrictions.

The move by Ottawa Mayor Jim Watson "reflects the serious danger and threat to the safety and security of residents posed by the ongoing demonstrations and highlights the need for support from other jurisdictions and levels of government," according to a statement from the city.

"It also provides greater flexibility within the municipal administration to enable the City of Ottawa to manage business continuity for essential services for its residents and enables a more flexible procurement process, which could help purchase equipment required by frontline workers and first responders," the city said.

Seven people were arrested in Ottawa on Sunday due to enforcement measures around the demonstration, according to a press release from the Ottawa Police Service.

"There are over 60 criminal investigations so far related to the demonstration," police said. "They are primarily for mischief, thefts, hate crimes and property damage."

Sunday marked the 10th straight day of the so-called "freedom convoy" protests, which began with truckers critical of a new rule that they must be vaccinated against COVID-19 to cross the United States-Canada border. The demonstrations have since grown into broader challenges to pandemic-related public health measures and opposition to Canadian Prime Minister Justin Trudeau.

Thousands of protesters have occupied the streets of Ottawa and other cities across Canada in support of the movement, paralyzing the capital's city center with traffic jams, nonstop noise and complaints of harassment. Protesters have said they won't leave until all COVID-19 vaccine mandates and restrictions are lifted nationwide. They are also calling for the removal of Trudeau's government, even though most of the public health measures were put in place by provincial governments.