Maryam Rajavi, the president-elect of the National Council of Resistance of Iran -- a coalition of dissident Iranian groups -- told European lawmakers on Wednesday that only "regime change by the people of Iran and the organized resisters" can ensure regional peace.

Israel's Friday surprise attack, Rajavi said, represents "the beginning of a critical new chapter, both in Iran's internal crisis and the broader dynamics of the region."

Rajavi also appeared to criticize Iranian monarchists who have rallied around opposition leader Reza Pahlavi -- the son of former Shah Mohammad Reza Pahlavi who was deposed by the 1979 Iranian Revolution -- who in recent days has called on Iranians to rise up against the government in Tehran.

"An alternative cannot be imposed from above, as was done a century ago when Britain installed a monarchy by appointment," Rajavi told lawmakers on Wednesday. "Nor can it be forced on the people like the 1953 coup d'état by the United States against the nationalist government of [former Prime Minister Mohammad] Mosaddegh."

"Had there been a legitimate nationalist and democratic government, the course of Iran's history -- and indeed the fate of this region -- would have been profoundly different," she said.

"Neither the shah, nor the mullahs," Rajavi added. "The people of Iran will accept no form of dictatorship and demand freedom."

The NCRI has been recognized as the political arm of the People's Mojahedin Organization of Iran -- known as the MEK -- which was a leftist revolutionary organization in Iran that fought a guerrilla war against the last shah and, after the 1979 revolution, the theocratic regime.

The NCRI has notable supporters among traditional Iran hawks in the U.S., with figures including former Vice President Mike Pence, former Secretary of State Mike Pompeo, former national security adviser John Bolton and others having spoken at their events in recent years.

The NCRI has called for the establishment of a democratic and secular republic in Iran. The MEK -- and by extension the NCRI -- were recognized as terrorist organizations by the U.S. until 2012.

Ayatollah Ali Khamenei, the supreme leader of Iran, warned in a post to X on Wednesday that a U.S. attack on Iran in support of Israel "without a doubt will cause irreparable damage."

"Intelligent people who know Iran and the nation and history of Iran will never speak to this nation in threatening language because the Iranian nation cannot be surrendered," Khamenei wrote.

In comments carried by Tasnim -- Iran's semi-official state news agency -- Khamenei said, "War will be met with war, bombing with bombing, and strike with strike. Iran will not submit to any demands or dictates.'

-ABC News' Ellie Kaufman

The International Atomic Energy Agency confirmed on Wednesday that Israeli strikes hit two centrifuge facilities at the TESA Karaj workshop and Tehran Research Center in the Iranian capital. Centrifuges are machines used to enrich uranium.

"At the Tehran site, one building was hit where advanced centrifuge rotors were manufactured and tested," the IAEA said in a post to X.

"At Karaj, two buildings were destroyed where different centrifuge components were manufactured," the IAEA said.

Both sites were previously under IAEA monitoring and verification under the JCPOA -- also known as the Iran nuclear deal -- negotiated and signed during President Barack Obama's administration.

President Donald Trump pulled the U.S. out of the JCPOA in 2018 during his first term in office.

-ABC News' Ellie Kaufman

Israeli Foreign Minister Gideon Sa'ar accused Iran on Wednesday of targeting civilian populations, saying Tehran is "making a mistake" by striking areas without military targets.

"I have no doubt that we will achieve our objectives in this operation in order to remove the existential threat," Sa'ar said at a meeting of more than 30 ambassadors to Israel.

Speaking in Bat Yam, south of Tel Aviv, at the site where an Iranian missile struck on Sunday, the minister said Israel was "determined to continue until we reach our objectives."

"There are no negotiations," he said. "The operation will continue until we achieve our objectives."

Russia has submitted "some proposals" to Iran and Israel that would end the war between the two countries and the proposals are being discussed, Russian President Vladimir Putin said in a speech Friday.

"We do not seek mediation, we just offer ideas. Not so long ago I spoke with Prime Minister Netanyahu, and with the President of Iran, with the President of the United States -- who, of course, are directly involved in all these processes -- presented them with my vision of possible progress towards resolving the situation," Putin said.

"Let's see, now our proposals are already being discussed, we have contacts with our Iranian friends on an almost daily basis. We'll see. I would very much like this, including our ideas, to be implemented," Putin said.

-ABC News' Tanya Stukalova and Anna Sergeeva