• Video
  • Shop
  • Culture
  • Family
  • Wellness
  • Food
  • Living
  • Style
  • Travel
  • News
  • Book Club
  • Newsletter
  • Privacy Policy
  • Your US State Privacy Rights
  • Children's Online Privacy Policy
  • Interest-Based Ads
  • Terms of Use
  • Do Not Sell My Info
  • Contact Us
  • © 2026 ABC News
  • Wellness

Is Drug Addiction Genetic?

Studies show that genes play a role in addiction.
Getty Images
ByLISA LOMBARDI, Health.com
September 25, 2014, 10:30 AM

— -- intro:In the new Vanity Fair cover story, Robert Downey Jr. talks about his struggles with drugs and his concern that he may have passed on an addictive personality to his son (his oldest child, Indio, was arrested for cocaine possession this summer and recently entered a guilty plea). The actor’s remarks raise the question: Is addiction actually genetic? To find out if you can, in fact, inherit a drug or alcohol problem, we talked to Akikur Mohamad, MD, a nationally-recognized addiction expert and founder of Inspire Malibu, a Los Angeles treatment center (which has not treated either Downey).

quicklist: 1category: Addiction and Genestitle: Robert Downey Jr. is correct: Genes play a role in addiction.url:text:Most studies show that 50% of your risk of becoming an addict is linked to your genes, says Dr. Mohamad: “Alcohol and drug addition is a chronic brain disease and just like most chronic diseases (asthma, diabetes, etc.), there is a strong genetic component.”

19 Medical Tests Everyone Needs

quicklist: 2category: Addiction and Genestitle: A child of an addict or alcoholic is more likely to get hooked.url:text:“Pick a dysfunction and and it’s a family problem,” the Iron Man star told Vanity Fair. It’s not a far-fetched statement. “Sons of alcoholic fathers are up to nine times as likely to develop drinking problems as the general population,” Dr. Mohamad notes. “Babies of alcoholics adopted into non-drinking homes have almost the same odds of alcoholism as they would if they’d stayed with their birth parents.”

quicklist: 3category: Addiction and Genestitle: Partying as a teen can set you up for future drug problems.url:text:Robert Downey Jr. has spoken openly about his father (director Robert Downey) introducing him to drugs at an early age, once telling People: “When my dad and I would do drugs together, it was like him trying to express his love for me in the only way he knew how.” Bad idea, say the experts. “Young people (from birth to their college years) have a much higher chance of incurring permanent brain damage from using alcohol or drugs, because their brains are still developing,” Dr. Mohamad explains. Not to mention, partying with the kids sends a powerful message that getting drunk or high is a smart idea.

Low Libido? 11 Drugs That Affect Your Sex Drive

quicklist: 4category: Addiction and Genestitle: Nurture also matters—in a surprising way.url:text:Nature and nurture play a role in drug abuse: “Your environment can trigger the genetic component,” explains Dr. Mohamad. For an alcoholic, simply passing a bar is enough to stimulate the brain receptors that turn on a craving for alcohol. And it can be a lifelong vulnerability. “Look at Philip Seymour Hoffman,” Dr. Mohamad points out. “After 20-plus years of being clean and sober, he reportedly snorted heroin several months before his death, and his addiction returned full-blown.”

quicklist: 5category: Addiction and Genestitle: These two steps help prevent the problem.url:text:“The vast majority of people who take a drink or even shoot heroin will not become addicts,” says Dr. Mohamad. (Only 10% of the population has a true addiction.) But if you have a family history, it’s key to make lifestyle tweaks. Two smart moves: Avoid friends who party hard and get counseling for any mental health issue that could cause you to “self medicate” with booze and pills. The encouraging news for the Downeys of the world: the cycle of addition can be broken, stresses Dr. Mohamad says: “Their fate isn’t sealed.”

15 Signs You May Have an Iron Deficiency

This article originally appeared on Health.com.

Up Next in Wellness—

Doctor explains why too much animal protein could be harmful

May 1, 2026

Cancer survivor meets donor who saved her life during Disney World 5K

May 1, 2026

Guitar teacher launches therapy program for Parkinson's patients

April 29, 2026

What to know about viral menopause treatment trend, according to a doctor

April 28, 2026

Shop GMA Favorites

ABC will receive a commission for purchases made through these links.

Sponsored Content by Taboola

The latest lifestyle and entertainment news and inspiration for how to live your best life - all from Good Morning America.
  • Contests
  • Terms of Use
  • Privacy Policy
  • Do Not Sell My Info
  • Children’s Online Privacy Policy
  • Advertise with us
  • Your US State Privacy Rights
  • Interest-Based Ads
  • About Nielsen Measurement
  • Press
  • Feedback
  • Shop FAQs
  • ABC News
  • ABC
  • All Videos
  • All Topics
  • Sitemap

© 2026 ABC News
  • Privacy Policy— 
  • Your US State Privacy Rights— 
  • Children's Online Privacy Policy— 
  • Interest-Based Ads— 
  • Terms of Use— 
  • Do Not Sell My Info— 
  • Contact Us— 

© 2026 ABC News