The TIME cover portrait featuring the Duke and Duchess of Sussex marks the first time the couple has formally posed together for a magazine cover shoot.
Photographed by Pari Dukovic, Prince Harry is seen wearing an all-black ensemble while Meghan rocks a white blouse and trousers.
The publication selected surprise pairings of its list members as well as guest contributors. Also, founder of World Central Kitchen José Andrés was selected to write about the royal couple.
"Springing into action is not the easy choice for a young duke and duchess who have been blessed through birth and talent, and burned by fame," wrote Andrés on Prince Harry and Meghan. "It would be much safer to enjoy their good fortune and stay silent. That’s not what Harry and Meghan do, or who they are... In a world where everyone has an opinion about people they don't know, the duke and duchess have compassion for the people they don't know. They don't just opine. They run toward the struggle."
Throughout the series of photos featured in Time Magazine, Prince Harry and Meghan are seen wearing forest green looks while posing in front of picturesque outdoor backdrops.
TIME editor-in-chief and CEO Edward Felsenthal in his letter to readers, said the royal couple has "catalyzed essential conversations on topics from mental health to misinformation."
In addition to the duke and duchess of Sussex cover, there are six others including Simone Biles, Billie Eilish, Kate Winslet, Cathy Park Hong, Jensen Huang and Ngozi Okonjo Oweala.
The list also includes features of rapper Lil Nas X, tennis star Naomi Osaka, Vice President Kamala Harris and a host of diverse notables.