\"What, like '15 Going on 50?'\" she joked. \"Let's simmer down. Let's leave well enough alone.\"

Catch and Release - 2006

Garner played a woman grieving the death of her fiance, who finds comfort in the most unlikely people, in this 2006 romantic comedy.

\"PHOTO:
Snap Stills/REX/Shutterstock
PHOTO: Timothy Olyphant and Jennifer Garner appear in the 2006 Sony Pictures film, "Catch and Release."
>

Juno - 2007

Garner starred in the hugely successful \"Juno\" as Vanessa Loring, the woman who adopts the baby of 16-year-old Juno MacGuff, played by Ellen Page.

\"PHOTO:
Snap Stills/REX/Shutterstock
PHOTO: Jennifer Garner, Jason Bateman and Ellen Page appear in the 2007 Fox Searchlight film, "Juno."
>

\"Scripts like this don’t come around that often,\" she told EW about the film at the time of its release.

Dallas Buyers Club - 2013

The actress played Dr. Eve Saks in the 2004 Academy Award-nominated film. Her costars Matthew McConaughey and Jared Leto won Oscars for their performances.

In an interview with Collider in 2013, she spoke about what she hoped to achieve when she went about playing the role of the doctor treating AIDS patients.

\"It sounds so corny, but I wanted to stay grounded so the boys could fly,\" she shared.

\"PHOTO:
Moviestore/REX/Shutterstock
PHOTO: Matthew McConaughey and Jennifer Garner in a scene from "Dallas Buyers Club."
>

\"I wanted to be the quiet one that was with them but not trying to match them or not trying to compete with them,\" she continued. \"Just be there to be kind of a quiet throughline so they could give these performances of their lives.\"

She also said she underwent a lengthy research process for the character. \"I went back and read everything I could find from ’81-’82 to about ’88-’89 –- all the medical journals, everything fed to the public, everything I could find having to do with H.I.V. and AIDS,\" she told Collider.

Love, Simon - 2018

Garner played Emily Spier, the mother to Simon, a closeted gay teenager who is struggling with his sexuality.

\"PHOTO:
Twentieth Century Fox via AP
PHOTO: Nick Robinson, Talitha Bateman, Jennifer Garner and Josh Duhamel in Twentieth Century Fox's "Love, Simon".
>

In one of the most touching scenes from the film, Garner's character delivers an impassioned monologue to Simon about acceptance and embracing his true self.

The moment moved everyone present on set while filming the scene.

\"Nick burst into tears,\" director Greg Berlianti told ABC News' Nightline. \"I looked around and all the crew was crying. It was in that moment, I think that we all kind of realized, this is a much more universal message than we thought.\"

Peppermint - 2018

One of Garner's latest roles shows her playing a woman who loses both her husband and daughter, leading her to go into hiding and eventually resurface to seek revenge.

\"PHOTO:
Michael Muller/STXfilms/AP
PHOTO: This cover image released by STXfilms shows Jennifer Garner in a scene from "Peppermint."
>

She posted a funny Instagram video of herself going to see the flick -- and her meltdown that followed.

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